Name : Piracetam
Trade Name : Dinagen, Myocalm, Nootropil, Qropi
- Piracetam is a prototype for Racetam supplements, which is a synthetic supplement group to provide cognitive ability to the brain.
- Piracetam has a history that is used to treat cognitive disorders. According to a meta-analysis of human studies, piracetam improves general cognitive when given to people in a state of cognitive decline, such as the condition of senility associated with aging. Although piracetam may be a useful supplement to increase longevity, piracetam offers limited benefits for healthy people.
- Healthy people who consume piracetam only experience little or no cognitive benefits. Although piracetam supplements in healthy people are still lacking research, preliminary evidence shows that piracetam is the most effective for the elderly. Piracetam supplementation has also been found to reduce the possibility of breathing difficulties in children.
- Piracetam increases the fluidity of cell membranes. This mechanism explains why piracetam is able to improve cognitive, especially in the elderly.
- Piracetam is as effective as aspirin when used to prevent blood clots, which makes it an additional intervention useful after cardiovascular trauma such as stroke
- Piracetam dissolves in water, and does not need to be taken along with food
- Many studies note high variability (inter-individual response differences)
- This drug (anecdote) is reported to be a non-stimulating drug (not stimulating the brain) and non-sedative (not a sedative)
Cognitive decline , has been investigated in a double-blind repeat study , the consistency of the study is very high. There seems to be an important reduction in the level of cognitive decline (or rehabiliation of age cognition) associated with high doses of Piracetam over time and in a general way. Piracetam is sometimes used as a comparison for cognitive decline.
Breathing difficulties , with strong effects, have been studied in a single double-blind study or multiple cohort studies, and have very high consistency of results. Very effective in reducing the difficulty of breathing in infants when used at appropriate doses, almost completely reduces breathing problems without side effects.
Aggressiveness , with little effect, but studies have been investigated in a single double-blind study or multiple cohort studies, and have very high consistency. In people with cognitive decline, Piracetam supplementation can reduce aggressiveness and agitation.
Memory, with its small effects, has been studied in a single double-blind study or multiple cohort studies, and has very high consistency . Increased memory with consumption of piracetam; proof of smoking is very limited to healthy individuals.
Stroke recovery , has been studied in a single double-blind study or multiple cohort studies, and has very high consistency of results . Not effective in one study where stroke recovery rates were assessed
Cognition has been studied only in uncontrolled or observational studies. There is no significant influence on cognition and nerves in healthy people
The standard dose for children is between 40-100mg per kilogram of body weight. This dose is intended for the treatment of respiratory disorders, although it has also been used for children with dyslexia. The lower dose limit range (40-50 mg / kg) is most commonly used.
The standard dose for adults is between 1,200-4,800mg a day. The biggest effective dose is 1,600mg, taken three times a day for a total daily dose of 4,800mg.
Rare and short-lasting piracetam side effects include anxiety, insomnia , drowsiness and agitation. It may be safe to consume up to 18 months in humans at a daily dose of 3.2 grams with a one-year study in outpatient Alzheimer’s patients using 8 grams of daily doses and not reporting any side effects. Piracetam also appears to have clinical use (and lack of side effects) when used in children and adolescents who experience respiratory problems with an oral dose of 50-100mg / kg body weight in children aged 5-60 months.
Piracetam seems to be quite non-toxic at commonly used doses, and some studies exceed the recommended dose (ie a dose of 4.8 grams a day) found no toxicity associated with piracetam